Navelbine®, one of the most recent chemotherapy drugs available today, is from a group of drugs known as plant alkaloids. These drugs work by stopping the cancer cells from separating into two new cells, therefore blocking the growth of the cancer. Navelbine may be used in tandem with another chemotherapy drug from a different family of medications.
The most common uses for Navelbine® are in treating breast cancer and non small-cell lung cancer. Fewer side effects are noted with this drug than with any other chemotherapy drug, especially those that were developed 20 to 30 years ago.
Clinical trials have also shown that approximately 25% of all mesothelioma patients who tried the drug had a positive response to it. This is about 5% higher than the success rate with most other chemotherapy drugs. In some cases, the disease stabilized for several months.
Treatment with Navelbine®
Navelbine® is injected through the vein or through a central line. However, capsules are also available. If your doctor has chosen the capsule form, they should be taken with a full glass of water and you should adhere strictly to the schedule given to you for the administration of this chemotherapy medication.
Your oncologist will determine the correct dosage of Navelbine® as well as the frequency of the treatments, based on the stage of your cancer, your body weight and size, and your overall health.
Side Effects of Navelbine®
As was previously stated, Navelbine® carries far fewer side effects than many other chemotherapy drugs. The most common are:
- Lowered resistance to infection
- Increased bruising or bleeding
- Nausea or vomiting
- Flu-like symptoms
- Tingling in the hands and feet (rare)
- Hair thinning (but rarely complete loss of hair)
You may experience some, all, or none of these side effects, but be sure to tell your doctor or medical team if you are experiencing any ongoing, disturbing side effects that may require immediate attention during your mesothelioma treatment with Navelbine®.
Manufactured by Pierre Fable Pharmaceuticals
- Chemocare.com, a program of the Scott Hamilton CARES initiative, Chemotherapy Drugs. http://www.chemocare.com/bio/navelbine.asp
- Martindale: The Complete Drug Reference (35th edition). Eds. Sweetman et al. Pharmaceutical Press, 2006.
- Cancer Backup. UK. http://www.cancerbackup.org.uk/Treatments/Chemotherapy/Individualdrugs/Vinorelbine
Last modified: December 24, 2010.