Bortezomib in Treating Patients With Malignant Pleural Mesothelioma

This study is currently recruiting patients.

Sponsored by:All Ireland Cooperative Oncology Research Group
Information provided:National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:NCT00513877

Purpose:

RATIONALE: Bortezomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

PURPOSE: This phase II trial is studying the side effects of bortezomib and how well it works in treating patients with malignant pleural mesothelioma.

Condition Intervention Phase
Malignant Mesothelioma
Drug: bortezomib
Procedure: quality-of-life assessment
Phase 2

Eligibility

Study Design: Allocation: Non-Randomized, Masking: Open Label, Primary Purpose: Treatment

Official Title: An Open Label Phase II Multicentre Clinical Trial of Single Agent Bortezomib in Patients With Malignant Pleural Mesothelioma

Enrollment Size: Both

Gender: 18 Years

Min. Age: N/A

Max. Age: No

Location and Contact Information

, B-9000
Universitair Ziekenhuis Gent, Ghent, B-9000, Belgium,
Status: Recruiting
Jan P. Van Meerbeeck, MD, PhD 32-9-332-2611 jan.vanmeerbeeck@ugent.be

, Ireland
Cork University Hospital, Cork, Ireland, ,
Status: Recruiting
Branislav Bystricky 353-21-492-0052 branislav.bystricky@mailp.hse.ie

, 24
Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital, Dublin, 24, Ireland,
Status: Recruiting
Ray McDermott, MD 353-1-414-2012 ray.mcdermott@amnch.ie

, 9
Beaumont Hospital, Dublin, 9, Ireland,
Status: Recruiting
Oscar Breathnach, MD 353-1-809-2373

, 8
St. James's Hospital, Dublin, 8, Ireland,
Status: Recruiting
Kenneth O'Byrne, MD 353-1-410-3752

, 7
Mater Misericordiae University Hospital, Dublin, 7, Ireland,
Status: Recruiting
Desmond N. Carney, MD 353-1-838-4444

, 4
St. Vincent's University Hospital, Dublin, 4, Ireland,
Status: Recruiting
John Crown, MD 011-353-1-269-5033

, Ireland
Galway University Hospital, Galway, Ireland, ,
Status: Recruiting
Maccon M. Keane, MD 353-91-524-222 maccon.keane@mailn.hse.ie

, 1066 BE
Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, 1066 BE, Netherlands,
Status: Recruiting
Paul Baas, MD, PhD 020-512-2958 p.baas@nki.nl

United Kingdom, England
Saint Bartholomew's Hospital, London, England, EC1A 7BE, United Kingdom
Status: Recruiting
Jeremy Steele, MD 44-207-601-7577

United Kingdom, England
Royal Marsden - Surrey, Sutton, England, SM2 5PT, United Kingdom
Status: Recruiting
Mary O'Brien, MD 44-20-8661-3276 mary.o'brien@rmh.nhs.uk

United Kingdom, Northern Ireland
Centre for Cancer Research and Cell Biology at Queen's University Belfast, Belfast, Northern Ireland, BT9 7BL, United Kingdom
Status: Recruiting
Dean A. Fennell, MD, PhD 44-28-9097-2960 d.fennell@qub.ac.uk

United Kingdom, Scotland
Beatson West of Scotland Cancer Centre, Glasgow, Scotland, G11 6NT, United Kingdom
Status: Recruiting
David J. Dunlop, MD 44-141-211-2837 dunlopdj@excute.com

Last modified: July 29 2010.