Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma

Sponsored by:Cancer and Leukemia Group B
Information provided:National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:NCT00509041

Purpose:

RATIONALE: Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

PURPOSE: This phase II trial is studying how well dasatinib works in treating patients with previously treated malignant mesothelioma.

Condition Intervention Phase
Malignant Mesothelioma
 Drug: dasatinib
Other: immunoenzyme technique
Other: immunohistochemistry staining method
Other: laboratory biomarker analysis
 Phase 2

Eligibility

Study Design: Treatment, Open Label

Official Title: A Phase II Study of Dasatinib (NSC #732517) in Patients With Previously Treated Malignant Mesothelioma

Enrollment Size: Both

Gender: 18 Years

Min. Age: N/A

Max. Age: No

Location and Contact Information

United States, California
Rebecca and John Moores UCSD Cancer Center, La Jolla, California, 92093-0658, United States
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United States, California
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, 94115, United States
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United States, Delaware
CCOP - Christiana Care Health Services, Newark, Delaware, 19713, United States
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United States, Delaware
Tunnell Cancer Center at Beebe Medical Center, Lewes, Delaware, 19958, United States
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United States, District of Columbia
Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, District of Columbia, 20007, United States
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United States, Florida
Florida Hospital Cancer Institute at Florida Hospital Orlando, Orlando, Florida, 32803-1273, United States
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United States, Georgia
Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center, Savannah, Georgia, 31403-3089, United States
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United States, Illinois
University of Chicago Cancer Research Center, Chicago, Illinois, 60637-1470, United States
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United States, Indiana
CCOP - Northern Indiana CR Consortium, South Bend, Indiana, 46601, United States
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United States, Indiana
Center for Cancer Therapy at LaPorte Hospital and Health Services, La Porte, Indiana, 46350, United States
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United States, Indiana
Elkhart General Hospital, Elkhart, Indiana, 46515, United States
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United States, Indiana
Fort Wayne Medical Oncology and Hematology, Fort Wayne, Indiana, 46845, United States
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United States, Indiana
Howard Community Hospital, Kokomo, Indiana, 46904, United States
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United States, Indiana
Memorial Hospital of South Bend, South Bend, Indiana, 46601, United States
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United States, Indiana
Saint Joseph Regional Medical Center, South Bend, Indiana, 46617, United States
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United States, Indiana
South Bend Clinic, South Bend, Indiana, 46617, United States
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United States, Maryland
Harry & Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center, Baltimore, Maryland, 21237, United States
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United States, Maryland
Union Hospital Cancer Program at Union Hospital, Elkton MD, Maryland, 21921, United States
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United States, Massachusetts
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts, 02115, United States
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United States, Massachusetts
Massachusetts General Hospital, Boston, Massachusetts, 02114, United States
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United States, Michigan
Lakeland Regional Cancer Care Center - St. Joseph, St. Joseph, Michigan, 49085, United States
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United States, Minnesota
Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, 55455, United States
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United States, Missouri
Arch Medical Services, Incorporated at Center for Cancer Care and Research, Saint Louis, Missouri, 63141, United States
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United States, Missouri
Missouri Baptist Cancer Center, Saint Louis, Missouri, 63131, United States
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United States, Nebraska
Methodist Estabrook Cancer Center, Omaha, Nebraska, 68114, United States
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United States, New Jersey
Cancer Institute of New Jersey at Cooper - Voorhees, Voorhees, New Jersey, 08043, United States
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United States, New York
SUNY Upstate Medical University Hospital, Syracuse, New York, 13210, United States
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United States, North Carolina
Duke Comprehensive Cancer Center, Durham, North Carolina, 27710, United States
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United States, North Carolina
Iredell Memorial Hospital, Statesville, North Carolina, 28677, United States
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United States, North Carolina
Kinston Medical Specialists, Kinston, North Carolina, 28501, United States
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United States, North Carolina
Wake Forest University Comprehensive Cancer Center, Winston-Salem, North Carolina, 27157-1096, United States
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United States, North Carolina
Wayne Memorial Hospital, Incorporated, Goldsboro, North Carolina, 27534, United States
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United States, Ohio
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center, Columbus, Ohio, 43210-1240, United States
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United States, South Carolina
CCOP - Greenville, Greenville, South Carolina, 29615, United States
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United States, Vermont
Fletcher Allen Health Care - University Health Center Campus, Burlington, Vermont, 05401, United States
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United States, Vermont
Mountainview Medical, Berlin, Vermont, 05602, United States
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United States, Virginia
Danville Regional Medical Center, Danville, Virginia, 24541, United States
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Last modified: February 09 2010.