Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma

Sponsored by:MolMed S.p.A.
Information provided:MolMed S.p.A.
ClinicalTrials.gov Identifier:NCT00484276

Purpose:

The main objective of the trial is to document the progression free survival (PFS) in advanced or metastatic malignant pleural mesothelioma patients treated with NGR-hTNF as single agent. Safety will be established by clinical and laboratory assessment according to NCI-CTC criteria.

Condition Intervention Phase
Malignant Pleural Mesothelioma
Drug: NGR-hTNF
Phase 2

Eligibility

Study Design: Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Official Title: NGR010: A Phase II Study of NGR-hTNF Administered as Single Agent Every 3 Weeks or Weekly in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma Previously Treated With no More Than One Systemic Therapeutic Regimen

Enrollment Size: Both

Gender: 18 Years

Min. Age: N/A

Max. Age: No

Location and Contact Information

, Milan
Istituto Clinico Humanitas, Rozzano, Milan, Italy,
Status:

, Italy
Istituto Europeo Oncologico, Milan, Italy, ,
Status:

, Italy
Istituto Nazionale dei Tumori, Milan, Italy, ,
Status:

, Italy
Fondazione San Raffaele del Monte Tabor, Milan, Italy, ,
Status:

Last modified: July 29 2010.