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Suberoylanilide Hydroxamic Acid Vorinostat, MK0683 Versus Placebo in Advanced Malignant Pleural Mesothelioma

This study is currently recruiting patients.

Purpose:

This is a study to determine the safety, tolerability, and anti-tumor effectiveness of an oral investigational drug, suberoylanilide hydroxamic acid, in the treatment of advanced malignant pleural mesothelioma.

Eligibility

Study Design: Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Official Title: A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Oral Suberoylanilide Hydroxamic Acid (Vorinostat, MK0683) in Patients With Advanced Malignant Pleural Mesothelioma Previously Treated With Systemic Chemotherapy.

Enrollment Size: Both

Gender: 18 Years

Min. Age: N/A

Max. Age: No

Location and Contact Information

United States, Colorado
Call for Information, Denver, Colorado, 80218, United States
Status: Recruiting

United States, Illinois
Call for Information, Chicago, Illinois, 60637-1460, United States
Status: Recruiting

United States, Illinois
Call for Information, Gurnee, Illinois, 60031, United States
Status: Recruiting

United States, Louisiana
Call for Information, New Orleans, Louisiana, 70121-0000, United States
Status: Recruiting

United States, Maryland
Call for Information, Annapolis, Maryland, 21401, United States
Status: Recruiting

United States, Michigan
Call for Information, Southfield, Michigan, 48075, United States
Status: Recruiting

United States, New York
Call for Information, New York, New York, 10021-6007, United States
Status: Recruiting

United States, Pennsylvania
Call for Information, Philadelphia, Pennsylvania, 19111, United States
Status: Recruiting

United States, Pennsylvania
Call for Information, Philadelphia, Pennsylvania, 19104, United States
Status: Recruiting

United States, Pennsylvania
Call for Information, Pittsburgh, Pennsylvania, 15232, United States
Status: Recruiting

United States, Texas
Call for Information, Houston, Texas, 77030, United States
Status: Recruiting

United States, Texas
Call for Information, Temple, Texas, 76508, United States
Status: Recruiting

, NSW 2142
Merck Sharp & Dohme (Australia) Pty Ltd., South Granville, NSW 2142, Australia,
Status: Recruiting
David Woolner 64-9-523-6075

, 1180
Merck Sharp & Dohme B.V., Bruxelles, 1180, Belgium,
Status: Recruiting
Nathalie Schrameijer 32-2-373-4310

Brazil, SP
Merck Sharp & Dohme Farmaceutica Ltda., Sao Paulo, SP, 04717-004, Brazil
Status: Recruiting
Jose Octavio P. Costa Filo 55-11-5189-7942

Canada, Quebec
Merck Frosst Canada Ltd., Kirkland, Quebec, H9H 3L1, Canada
Status: Recruiting
Michel Cimon 514-428-2605

, 10 010
Merck Sharp & Dohme IDEA, Inc., Zagreb, 10 010, Croatia,
Status: Recruiting
Goranka Glad Scherr 385 1 66 44 336

, Egypt
Merck Sharp & Dohme Scientific Office, Cairo, Egypt, ,
Status: Recruiting
Sherif Canaan 202-2417-2320

, 85540
Msd Sharp & Dohme Gmbh, Haar, 85540, Germany,
Status: Recruiting
Thomas Lang 49-89-4561-1536

, 110011
MSD Pharmaceuticals Private Ltd., New Delhi, 110011, India,
Status: Recruiting
Swashraya Shah 91-124-464-7338

, 49192
Merck Sharp & Dohme Co. Ltd., Petah Tikva, 49192, Israel,
Status: Recruiting
Raanan Cohen 972-3-9274005

, 191
Merck Sharp & Dohme (Italia) S.P.A., Roma, 191, Italy,
Status: Recruiting
Gianfranco Botta 39 06 36 191187

Japan, Chiyodaku
Merck Ltd., Japan, Tokyo, Chiyodaku, 102-8667, Japan
Status: Recruiting
Tadaaki Taniguchi 81-3-6272-1547

Mexico, D.f.
Merck Sharp & Dohme De Mexico, S.A. De C.V., Mexico, D.f., 1090, Mexico
Status: Recruiting
Juan Diaz 52-55-5481-9825

, 2031 BN
Merck Sharp & Dohme B.V., Haarlem, 2031 BN, Netherlands,
Status: Recruiting
Caroline Doornebos 31-23-515-3362

, New Zealand
Merck Sharp & Dohme (New Zealand) Ltd.,, Auckland, New Zealand, ,
Status: Recruiting
David Woolner 64-9523-6075

Peru, Lima
Merck Sharp & Dohme, Peru S.R.L., Surquillo, Lima, LIMA 34, Peru
Status: Recruiting
Jorge Vinces 511-411-5933

, 2770-192
Merck Sharp & Dohme Lda, Paco D`arcos, 2770-192, Portugal,
Status: Recruiting
Lai Hung Jen 351-21-4465821

South Africa, Gauteng
MSD (Pty) LTD South Africa, Midrand, Gauteng, 1685, South Africa
Status: Recruiting
Beverley Cowper 27 11 655-3036

, 28027
Merck Sharp & Dohme De Espana, S.A.E., Madrid, 28027, Spain,
Status: Recruiting
Jorge Gonzalez-Esteban 34-91-3210-728

, 192 07
Merck Sharp & Dohme (Sweden) AB, Sollentuna, 192 07, Sweden,
Status: Recruiting
Roger Juhlin 46-8-626-1 458

Turkey, Istanbul
Merck Sharp & Dohme Ilaclari Ltd. Sti, Istinye, Istanbul, 34460, Turkey
Status: Recruiting
Meltem Telaferli 90 212 365 5354

United Kingdom, Hertfordshire
Merck Sharp & Dohme Ltd., Hoddesdon, Hertfordshire, EN11 9BU, United Kingdom
Status: Recruiting
Paul Robinson 44 1992 452396

Last modified: July 29 2010.